Perinatal Laboratory

Perinatal Laboratory

Research group

Research Areas

Our main focus of research is to understand and describe different aspects of the preterm delivery process and child outcome, to explore the genetics and gene by environment interaction of timing of birth (including preterm delivery
and post term delivery).

We also aiming to explore basic epidemiological relations regarding preterm delivery and child outcome and to develop and test different methods for improving fetal medicine.
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Cohort Based Genetic Studies

In genome-wide association studies we investigate genetic code of thousands of mothers and their children in order to find the genes that play role in determining the duration of gestation. The knowledge of such genes can explain the biology behind the timing of birth and parturition mechanisms. In gene-environment interaction studies we try to identify women whose genetic profile makes their gestation extremely sensitive to common environmental exposures, such as caffeine intake, smoking, vitamins, microelements, probiotic products. Such women should receive personalized recommendations for their diet and supplements use during pregnancy.
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Our genetic team: Chris Flately, Pol Solé Navais.

Register Based Epidemiology Studies

We explore incidence/prevalence rates, comorbidities and heritability estimates of various pregnancy phenotypes. We perform an in-depth investigation of common risk factors and predictors of preterm delivery such as maternal height, age, BMI, parity.
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Our epidemiology team: Verena Sengpiel, Linda Englund-Ögge, Patricia Johansson, Mahsa Nordqvist, Tomas Fritz.

Cohort Based Biomarker Studies

Cohort Study and its large cohort of women has created unique conditions for nutritional studies. We explore the relationship between various dietary environmental exposures during the pregnancy and the risk of delivering preterm. These studies generate hypotheses of causality which can later be tested in the randomized clinical trials.
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Our nutrition team: Verena Sengpiel, Linda Englund-Ögge, Malin Barman.

Cohort Based Nutritional Studies

​Cohort Study and its large cohort of women has created unique conditions for nutritional studies. We explore the relationship between various dietary environmental exposures during the pregnancy and the risk of delivering preterm. These studies generate hypotheses of causality which can later be tested in the randomized clinical trials.
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Our nutrition team: Verena Sengpiel, Linda Englund-Ögge, Malin Barman, Mahsa Nordqvist.

Activities

The Nordic Network of Fetal Medicine

The Nordic Network of Fetal Medicine, NNFM, was held at Sahlgrenska University Hospital spring 2015. For latest news visit nnfm.org

The European Spontaneous Preterm Birth Congress

The 2nd European Spontaneous Preterm Birth Congress, ESPBC, took place in Gothenburg Sweden in May 26th-28th 2016. The congress, an event held every second year, is intended to be a conference venue for experts from all over of the world with special focus on the European situation. The ESPBC is organized with FIGO participation.

The main objective of the meeting is to give the international scientific community in the field of Spontaneous Preterm Birth the opportunity to give and exchange scientific information on the current knowledge and get updates on the last findings.
For more information and latest news visit espbc.eu

FIGO & MOD

We are also happy to continuing having a close collaboration with the leadership
of both The International Federation of Gynecology and Obstetrics (FIGO) and
The March of Dimes (MOD), in order to develop a program for action to promote
the prevention of preterm delivery world-wide.
For more information about the organisations, visit FIGO or MOD.

Partnerships

The Perinatal Laboratory group are currently working with a variety of international organizations and public institutions. The most important partnerships are listed below.
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  • The National Board of Health and Welfare
  • Statistics Sweden
  • World health organisation/PMNCH (WHO)
  • March Of Dimes (MOD)
  • World Health Organisation (WHO)
  • The International Federation of Gynecology and Obstetrics (FIGO)
  • European Spontaneous Preterm Birth Congress (ESPBC)
  • Nordic Network of Fetal Medicine (NNFM)
  • Preterm Birth International Collaborative (PREBIC)
  • The Norwegian Institute of Public Health (NIPH)

Funding

Fundings are the main important thing for scientific development and to take the research to the level we want. Without fundings we would not have the opportunity to progress and look for solutions. Our group obtains grants by several international and national organizations, foundations and research councils. The funding is mainly received in international competitions. Below is a list of important financial support.

Publications by Category

Cohort Based Genetic Studies

  1. van der Valk, R.J. et al. A novel common variant in DCST2 is associated with length in early life and height in adulthood. Hum Mol Genet (2015).
  2. Rietveld, C.A. et al. GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013).
  3. Myking, S. et al. X-chromosomal maternal and fetal SNPs and the risk of spontaneous preterm delivery in a Danish/Norwegian genome-wide association study. PLoS One (2013).
  4. Tyrrell, J. et al. Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) interacts with maternal self-reported smoking status during pregnancy to influence birth weight. Hum Mol Genet (2012).
  5. Paternoster, L. et al. Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis. Nat Genet (2012).

Register Based Epidemiology Studies

  1. Khatibi, A. et al. Prepregnancy maternal body mass index and preterm delivery. Am J Obstet Gynecol (2012).
  2. Morken, N.H. et al. Subgroups of preterm delivery in the Norwegian Mother and Child Cohort Study. Acta Obstet Gynecol Scand (2008).
  3. Morken, N.H. et al. Outcomes of preterm children according to type of delivery onset: a nationwide population-based study. Paediatr Perinat Epidemiol (2007).
  4. Morken, N.H. et al. Fetal growth and onset of delivery: a nationwide population-based study of preterm infants. Am J Obstet Gynecol (2006).
  5. Langhoff-Roos, J. et al. Spontaneous preterm delivery in primiparous women at low risk in Denmark: population based study. BMJ (2006).

Cohort Based Biomarker Studies

  1. Kacerovsky, M. et al. Bedside assessment of amniotic fluid interleukin-6 in preterm prelabor rupture of membranes. Am J Obstet Gynecol (2014).
  2. Cobo, T. et al. Umbilical cord blood IL-6 as predictor of early-onset neonatal sepsis in women with preterm prelabour rupture of membranes. PLoS One (2013).
  3. Tsiartas, P. et al. Prediction of spontaneous preterm delivery in women with threatened preterm labour: a prospective cohort study of multiple proteins in maternal serum. BJOG (2012).
  4. Holst, R.M. et al. Prediction of spontaneous preterm delivery in women with preterm labor: analysis of multiple proteins in amniotic and cervical fluids. Obstet Gynecol (2009).
  5. Ruetschi, U. et al. Proteomic analysis using protein chips to detect biomarkers in cervical and amniotic fluid in women with intra-amniotic inflammation. J Proteome Res (2005).
  6. Musilova, I. et al. Ureaplasma species and Mycoplasma hominis in cervical fluid of pregnancies complicated by preterm prelabor rupture of membranes. J Matern Fetal Neonatal Med (2014).
  7. Hakansson, S. et al. Real-time PCR-assay in the delivery suite for determination of group B streptococcal colonization in a setting with risk-based antibiotic prophylaxis. J Matern Fetal Neonatal Med (2014).
  8. Kacerovsky, M. et al. The impact of the microbial load of genital mycoplasmas and gestational age on the intensity of intraamniotic inflammation. Am J Obstet Gynecol (2012).
  9. Kacerovsky, M. et al. The microbial load with genital mycoplasmas correlates with the degree of histologic chorioamnionitis in preterm PROM. Am J Obstet Gynecol (2011).
  10. Jacobsson, B. et al. Quantification of Ureaplasma urealyticum DNA in the amniotic fluid from patients in PTL and pPROM and its relation to inflammatory cytokine levels. Acta Obstet Gynecol Scand (2009).

Cohort Based Nutritional Studies

  1. Sengpiel, V. et al. Folic acid supplementation, dietary folate intake during pregnancy and risk for spontaneous preterm delivery: a prospective observational cohort study. BMC Pregnancy Childbirth (2014).
  2. Englund-Ogge, L. et al. Maternal dietary patterns and preterm delivery: results from large prospective cohort study. BMJ (2014).
  3. Sengpiel, V. et al. Maternal caffeine intake during pregnancy is associated with birth weight but not with gestational length: results from a large prospective observational cohort study. BMC Med (2013).
  4. Myhre, R. et al. Intakes of garlic and dried fruits are associated with lower risk of spontaneous preterm delivery. J Nutr (2013).
  5. Englund-Ogge, L. et al. Association between intake of artificially sweetened and sugar-sweetened beverages and preterm delivery: a large prospective cohort study. Am J Clin Nutr (2012).
  6. Myhre, R. et al. Intake of probiotic food and risk of spontaneous preterm delivery. Am J Clin Nutr (2011). 

Animal Model Studies

  1. Hellgren, G. et al. Proliferative retinopathy is associated with impaired increase in BDNF and RANTES expression levels after preterm birth. Neonatology (2010).
  2. Wang, X. et al. Effects of intrauterine inflammation on the developing mouse brain. Brain Res (2007).
  3. Wang, X. et al. Disruption of interleukin-18, but not interleukin-1, increases vulnerability to preterm delivery and fetal mortality after intrauterine inflammation. Am J Pathol (2006).

All Publications

Published articles in international journals (* part of my thesis)
  1. *Jacobsson B, Hagberg G, Hagberg B, Ladfors L, Niklasson A, Hagberg H. Cerebral palsy in preterm infants: a population-based case-control study of antenatal and intrapartal risk factors. Acta Paediatr. 91. 946-51. 2002. *
  2. Jacobsson B, Pernevi P, Chidekel L, Jorgen Platz-Christensen J. Bacterial vaginosis in early pregnancy may predispose for preterm birth and postpartum endometritis. Acta Obstet Gyn Scan. 81. 1006-1010. 2002.
  3. *Jacobsson B, Holst RM, Mattsby-Baltzer I, Nikolaitchouk N, Wennerholm UB, Hagberg H. Interleukin-18 in cervical mucus and amniotic fluid: relationship to microbial invasion of the amniotic fluid, intra-amniotic inflammation and preterm delivery. BJOG: Int J Obstet Gy. 110. 598-603. 2003.
  4. *Jacobsson B, Mattsby-Baltzer I, Andersch B, Bokstrom H, Holst RM, Nikolaitchouk N, Hagberg H. Microbial invasion and cytokine response in amniotic fluid in a Swedish population of women with preterm prelabor rupture of membranes. Acta Obstet Gyn Scan. 82. 423-31. 2003.
  5. *Jacobsson B, Mattsby-Baltzer I, Andersch B, Bokstrom H, Holst RM, Wennerholm UB, Hagberg H. Microbial invasion and cytokine response in amniotic fluid in a Swedish population of women in preterm labor. Acta Obstet Gyn Scan. 82. 120-8. 2003.
  6. *Jacobsson B, Holst RM, Wennerholm UB, Andersson B, Lilja H, Hagberg H. Monocyte chemotactic protein-1 in cervical and amniotic fluid: relationship to microbial invasion of the amniotic cavity, intra-amniotic inflammation and preterm delivery. Am J Obstet Gynecol. 189. 1161-7. 2003.
  7. Jacobsson B, Ladfors L, Milsom I. Advanced maternal age and adverse perinatal outcome. Obstet Gynecol. 104. 727-33. 2004.
  8. Holst RM, Mattsby-Baltzer I, Wennerholm UB, Hagberg H, Jacobsson B. Interleukin-6 and interleukin-8 in cervical fluid in a population of Swedish women in preterm labor: relation to microbial invasion of the amniotic fluid, intra-amniotic inflammation and preterm delivery. Acta Obstet Gyn Scan. 84. 551-7. 2005.
  9. Morken N, Källen K, Hagberg H, Jacobsson B. Preterm birth in Sweden 1973-2001: rate, subgroups and effect of changing patterns in multiple births, maternal age and smoking. Acta Obstet Gyn Scan. 84. 558-65. 2005.
  10. Jacobsson B, Holst RM, Andersson B, Hagberg H. Monocyte chemotactic protein-2 and -3 in amniotic fluid: relationship to microbial invasion of the amniotic cavity, intra-amniotic inflammation and preterm delivery Acta Obstet Gyn Scan. 84. 566-71. 2005.
  11. Almström E, Bejlum C, Buchhave P, Clausen J, Dahle L, Froding I, Herbst A, Itzel E, Jacobsson B, Källén K, Laurin J, Leyon J, Lindholm-Jansson L, Lindqvist A, Lindström Ann-Marie, Olofsson P, Pettersson K, Rydhström H, Stale H, Söderlund J, Walles B, Wennerholm U-B, Westgren M, Wolff K. Term breech delivery in Sweden: mortality relative to fetal presentation and planned mode of delivery. Acta Obstet Gyn Scan. 84. 593-601. 2005.
  12. Jacobsson B, Mattsby-Baltzer I, Hagberg H. Interleukin-6 and interleukin-8 in cervical and amniotic fluid: relationship to microbial invasion of the chorioamniotic membranes. BJOG: Int J Obstet Gy. 112. 719-24. 2005.
  13. Bax M, Goldstein M, Rosenbaum P, Leviton A, Paneth N, Dan B, Jacobsson B, Diane Damiano. Proposed definition and classification of cerebral palsy. Dev Med Child Neurol. 47. 571-576. 2005.
  14. Rüetschi U, Rosén A, Karlsson G, Zetterberg H, Rymo L, Hagberg H, Jacobsson B. Proteomic analysis using protein chips to detect biomarkers in cervical and amniotic fluid in women with intra-amniotic inflammation. J Proteome Res. 4. 2236-2242. 2005.
  15. Thorsen P, Vogel I, Olsen J, Jeune B, Westergaard JG, Jacobsson B, Møller BR. Bacterial vaginosis in early pregnancy is associated with low birth weight and small for gestational age, but not with spontaneous preterm birth: A population-based study on Danish women. J Matern-Fetal Neo M. 19.1-7. 2006.
  16. Langhoff-Roos J, Kesmodel U, Jacobsson B, Rasmussen S, Vogel I. Spontaneous preterm delivery in primiparous women at low risk in Denmark: population based study. BMJ. 332. 937-9. 2006.
  17. Menon R, Velez DR, Simhan H, Ryckman K, Jiang L, Thorsen P, Vogel I, Jacobsson B, Merialdi M, Williams SM, Fortunato SJ. Multilocus interactions at maternal tumor necrosis factor-alpha, tumor necrosis factor receptors, interleukin-6 and interleukin-6 receptor genes predict spontaneous preterm labor in European-American women. Am J Obstet Gynecol. 194. 1616-24. 2006.
  18. Morken NH, Källen K, Jacobsson B. Fetal growth and onset of delivery: a nationwide population-based study in preterm infants. Am J Obstet Gynecol. 195. 154-61. 2006.
  19. Vogel I, Thorsen P, Hogan V, Schieve L. Jacobsson B, Ferre C. The Joint Effect of Ureaplasma Urealyticum and Bacterial Vaginosis on Adverse Pregnancy Outcomes. Acta Obstet Gyn Scan. 85. 778-85. 2006.
  20. Thorsen P, Vogel I, Molsted K, Jacobsson B, Arpi M, Møller BR, Jeune B. Risk factors for bacterial vaginosis in pregnancy: a population-based study on Danish women. Acta Obstet Gyn Scan. 85. 906-11. 2006.
  21. Wang X, Hagberg H, Mallard C, Zhu C, Hedtjärn M, Tiger CF, Eriksson K, Rosén A, Jacobsson B. Disruption of Interleukin-18, but Not Interleukin-1, Increases Vulnerability to Preterm Delivery and Fetal Mortality after Intrauterine Inflammation. Am J Pathol. 169(3): 967-76. 2006.
  22. Menon R, Velez DR, Thorsen P, Vogel I, Jacobsson B, Williams SM, Fortunato SJ. Ethnic differences in key candidate genes for spontaneous preterm birth: TNF-alpha and its receptors.
    Hum Hered. 62. 107-18. 2006.
  23. Holst RM, Jacobsson B, Hagberg H, Wennerholm UB. Cervical length in women in preterm labor with intact membranes: relationship to intra-amniotic inflammation/ microbial invasion, cervical inflammation and preterm delivery. Ultrasound Obst Gyn. 28. 768-74. 2006.
  24. Vogel I, Thorsen P, Jeune B, Jacobsson B, Ebbesen N, Arpi M, Bremmelgaard A, Møller B. Acquisition and elimination of bacterial vaginosis in pregnancy: a Danish population based study. Infectious Diseases in Obstetrics and Gynecology. 14. 946. 2006.
  25. Rosenbaum P, Paneth N, Leviton A, Goldstein M, Bax M, Damiano D, Dan B, Jacobsson B. A report: the definition and classification of cerebral palsy April 2006. Dev Med Child Neurol. 109. 8-14. 2007.
  26. Pennell CE, Jacobsson B, Williams SM, Buus RM, Muglia LJ, Dolan SM, Morken NH, Ozcelik H, Lye SJ, PREBIC Genetics Working Group, Relton C. Genetic Epidemiologic Studies of Preterm Birth – Guidelines for research. Am J Obstet Gynecol. 196(2): 107-18. 2007.
  27. Magnusson-Olsson AL, Lager S, Jacobsson B, Jansson T, Powell TL. Effect of maternal triglycerides and free fatty acids on placental LPL in cultured primary trophoblast cells and in a case of maternal LPL deficiency. Am J Physiol-Endoc M. 293. E24-30. 2007.
  28. Wang X, Hagberg H, Zhu C, Jacobsson B, Mallard C. Effects of intrauterine inflammation on the developing mouse brain. Brain Res. 1144. 180-5. 2007.
  29. Menon R, Thorsen P, Vogel I, Jacobsson B, Williams S, Fortunato SJ. Increased bioavailability of TNF-alpha in African Americans during in vitro infection: predisposing evidence for immune imbalance. Placenta. 28. 946-50. 2007.
  30. Morken NH, Källen K, Jacobsson B. Outcomes of preterm children according to type of delivery onset: a nationwide population-based study. Paediatr Perinat Ep. 21. 458-64. 2007.
  31. Holst RM, Laurini R, Jacobsson B, Samuelsson E, Sävman K, Doverhag C, Wennerholm UB, Hagberg H. Expression of cytokines and chemokines in cervical and amniotic fluid: relationship to histological chorioamnionitis. J Matern-Fetal Neo M. 20. 885-93. 2007.
  32. Håkansson S, Axemo P, Bremme K, Bryngelsson AL, Wallin MC, Ekström CM, Granlund M, Jacobsson B, Källén K, Spetz E, Tessin I; Swedish Working Group For The Prevention of Perinatal Group B Streptococcal Infections. Group B streptococcal carriage in Sweden: a national study on risk factors for mother and infant colonisation. Acta Obstet Gyn Scan. 87. 50-8. 2008.
  33. Johanzon M, Odesjö H, Jacobsson B, Sandberg K, Wennerholm UB. Extreme preterm birth: onset of delivery and its effect on infant survival and morbidity. Obstet Gynecol. 111. 42-50. 2008.
  34. Ekelund CK, Vogel I, Skogstrand K, Thorsen P, Hougaard DM, Langhoff-Roos J, Jacobsson B. Interleukin-18 and Interleukin-12 in maternal serum and spontaneous preterm delivery. J Reprod Immunol. 77. 179-85. 2008.
  35. Menon R, Thorsen P, Vogel I, Jacobsson B, Morgan N, Jiang L, Li C, Williams SM, Fortunato SJ. Racial disparity in amniotic fluid concentrations of tumor necrosis factor (TNF)-alpha and soluble TNF receptors in spontaneous preterm birth. Am J Obstet Gynecol. 198. 533.e1-10. 2008.
  36. Skogstrand K, Ekelund CK, Thorsen P, Vogel I, Jacobsson B, Nørgaard-Pedersen B, Hougaard DM. Effects of blood sample handling procedures on measurable inflammatory markers in plasma, serum and dried blood spot samples. J Immunol Methods. 336. 78-84. 2008.
  37. Kvarnstrand L, Milsom I, Lekander T, Druid H, Jacobsson B. Maternal fatalities, fetal and neonatal deaths related to motor vehicle crashes during pregnancy: a national population-based study. Acta Obstet Gyn Scan. 87. 946-52. 2008.
  38. Jacobsson B, Ahlin K, Francis A, Hagberg G, Hagberg H, Gardosi J. Cerebral palsy and restricted growth status at birth: population-based case-control study. BJOG: Int J Obstet Gy. 115. 1250-5. 2008.
  39. Nielsen LF, Schendel D, Grove J, Hvidtjørn D, Jacobsson B, Jossiassen T, Vestergaard M, Uldall P, Thorsen P. Asphyxia-related riskfactors and their timing in Spastic Cerebral Palsy. BJOG: Int J Obstet Gy. 115. 1518-28. 2008.
  40. Morken NH, Magnus P, Jacobsson B. Subgroups of preterm delivery in the Norweigan Mother and Child Cohort Study. Acta Obstet Gyn Scan. 87 .1374-7. 2008.
  41. Morken NH, Vogel I, Kallen K, Skjaerven R, Langhoff-Roos J, Kesmodel US, Jacobsson B. Reference population for international comparisons and time trend surveillance of preterm delivery proportions in three countries. BioMed Central Women’s Health. 8.16. 2008.
  42. Hvidtjørn D, Schieve L, Schendel D, Jacobsson B, Sværke C, Thorsen P. Cerebral palsy, autism spectrum disorders and developmental delay in children born after assisted conception: a systematic review and meta-analysis. Arch Pediat Adol Med. 163. 72-83. 2009.
  43. Jacobsson B, Aaltonen R, Rantakokko-Jalava K. Morken NH, Alanen A. Quantification of Ureaplasma urealyticum DNA in the amniotic fluid from patients in PTL and pProm and its relation to inflammatory cytokine levels. Acta Obstet Gyn Scan. 88. 63-70. 2009.
  44. Holst RM, Hagberg H, Wennerholm UB, Skogstrand K, Thorsen P, Jacobsson B. Prediction of Spontaneous preterm delivery in women with preterm labor: analysis of multiple proteins in amniotic and cervical fluids. Obstet Gynecol 114. 268-77. 2009.
  45. Ryckman KK, Morken NH, White MJ, Velez DR, Menon R, Fortunato SJ, Magnus P, Williams SM, Jacobsson B. Maternal and Fetal Genetic Associations of PTGER3 and PON1 with Preterm Birth. PLoS One. 5 .e9040. 2010.
  46. Hvidtjørn D, Grove J, Schendel D, Sværke C, Schieve LA, Uldall P, Ernst E, Jacobsson B, Thorsen P. Multiplicity and early gestational age contribute to an increased risk of cerebral palsy from assisted conception: a population-based cohort study. Hum Reprod. 25. 2115-23. 2010.
  47. Granlund M, Axemo P, Bremme K, Bryngelsson AL, Carlsson Wallin M, Ekström CM, Håkansson S, Jacobsson B, Källén K, Spetz E, Tessin I; Swedish Working Group For The Prevention of Perinatal Group B Streptococcal Infections. Antimicrobial resistance in colonizing Group B Streptococci before the implementation of a Swedish intrapartum antibiotic prophylaxis program. Eur J Clin Microbiol: official publication of the European Society of Clinical Microbiology. 29. 1195-201. 2010.
  48. Hellgren G, Willett K, Engström E, Thorsen P, Hougaard DM, Jacobsson B, Hellstrom A, Lofqvist C. Proliferative retinopathy is associated with impaired increase in BDNF and RANTES expression levels after preterm birth. Neonatology. 98. 409-18. 2010.
  49. Holst RM, Hagberg H, Wennerholm UB, Skogstrand K, Thorsen P, Jacobsson B. Prediction of microbial invasion of the amniotic cavity in women with preterm labour: analysis of multiple proteins in amniotic and cervical fluids. BJOG: Int J Obstet Gy. 118. 240-9. 2011.
  50. Myhre R, Bransæter AL, Myking S, Gjessing H, Sengpiel V, Meltzer HM, Haugen M, Jacobsson B. Intake of probiotic food and risk of spontaneous preterm delivery. Am J Clin Nutr. 93. 151-7. 2011.
  51. Himmelmann K, Ahlin K, Jacobsson B, Cans C, Thorsen P. Risk factors for cerebral palsy in children born at term. Acta Obstet Gyn Scan. Oct;90(10):1070-81. 2011
  52. Brantsæter AL, Myhre R, Haugen M, Myking S, Sengpiel V, Magnus P, Jacobsson B, Meltzer HM. Intake of probiotic food and risk of preeclampsia in primiparous women: the Norwegian Mother and Child Cohort study. Am J Epidemiol. Oct 1;174(7):807-15. 2011.
  53. Myking S, Myhre R, Gjessing HK, Morken NH, Sengpiel V, Williams SM, Ryckman KK, Magnus P, Jacobsson B. Candidate gene analysis of spontaneous preterm delivery: New insights from re-analysis of a case-control study using case-parent triads and control-mother dyads. BMC Med Genet. Dec 30;12(1):174. 2011.
  54. Morken NH, Gunnes N, Magnus P, Jacobsson B. Risk of spontaneous preterm delivery in a low-risk population: the impact of maternal febrile episodes, urinary tract infection, pneumonia and ear-nose-throat infections. Eur J Obstet Gyn R B. Dec;159(2):310-4. 2011.
  55. Paternoster L, Standl M, Chen CM, Ramasamy A, Bønnelykke K, Duijts L, Ferreira MA, Alves AC, Thyssen JP, Albrecht E, Baurecht H, Feenstra B, Sleiman PM, Hysi P, Warrington NM, Curjuric I, Myhre R, Curtin JA, Groen-Blokhuis MM, Kerkhof M, Sääf A, Franke A, Ellinghaus D, Fölster-Holst R, Dermitzakis E, Montgomery SB, Prokisch H, Heim K, Hartikainen AL, Pouta A, Pekkanen J, Blakemore AI, Buxton JL, Kaakinen M, Duffy DL, Madden PA, Heath AC, Montgomery GW, Thompson PJ, Matheson MC, Le Souëf P; Australian Asthma Genetics Consortium (AAGC), St Pourcain B, Smith GD, Henderson J, Kemp JP, Timpson NJ, Deloukas P, Ring SM, Wichmann HE, Müller-Nurasyid M, Novak N, Klopp N, Rodríguez E, McArdle W, Linneberg A, Menné T, Nohr EA, Hofman A, Uitterlinden AG, van Duijn CM, Rivadeneira F, de Jongste JC, van der Valk RJ, Wjst M, Jogi R, Geller F, Boyd HA, Murray JC, Kim C, Mentch F, March M, Mangino M, Spector TD, Bataille V, Pennell CE, Holt PG, Sly P, Tiesler CM, Thiering E, Illig T, Imboden M, Nystad W, Simpson A, Hottenga JJ, Postma D, Koppelman GH, Smit HA, Söderhäll C, Chawes B, Kreiner-Møller E, Bisgaard H, Melén E, Boomsma DI, Custovic A, Jacobsson B, Probst-Hensch NM, Palmer LJ, Glass D, Hakonarson H, Melbye M, Jarvis DL, Jaddoe VW, Gieger C; Genetics of Overweight Young Adults (GOYA) Consortium, Strachan DP, Martin NG, Jarvelin MR, Heinrich J, Evans DM, Weidinger S; EArly Genetics & Lifecourse Epidemiology (EAGLE) Consortium. Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis. Nat Genet. Dec 25;44(2):187-92. 2011.
  56. Kacerovsky M, Pliskova L, Bolehovska R, Musilova I, Hornychova H, Tambor V, Jacobsson B. The microbial load with genital mycoplasmas correlates with the degree of histologic chorioamnionitis in preterm PROM. Am J Obstet Gynecol. Sep;205(3):213.e1-7. 2011.
  57. Myatt L, Eschenbach DA, Lye SJ, Mesiano S, Murtha AP, Williams SM, Pennell CE; International Preterm Birth Collaborative Pathways and Systems Biology Working Groups (collaborators: Gravett M, Jacobsson B, Sengpiel V, Uldbjerg N, Ang W, Ekman-Ordeberg G, Olson D, Helmig RB, Becher N, Chudzik A, Drobek CO). A standardized template for clinical studies in preterm birth. Reprod Sci. May;19(5):474-82. 2012.
  58. Kacerovsky M, Pliskova L, Bolehovska R, Skogstrand K, Hougaard DM, Tsiartas P, Jacobsson B. The impact of the microbial load of genital mycoplasmas and gestational age on the intensity of intraamniotic inflammation. Am J Obstet Gynecol. Apr;206(4):342.e1-8. 2012.
  59. Tsiartas P, Holst RM, Wennerholm UB, Hagberg H, Hougaard DM, Skogstrand K, Pearce BD, Thorsen P, Kacerovsky M, Jacobsson B. Prediction of spontaneous preterm delivery in women with threatened preterm labor: a prospective cohort study of multiple proteins in maternal serum.
    Jun;119(7):866-73. 2012.
  60. Kacerovsky M, Andrys C, Drahosova M, Musilova I, Hornychova H, Lesko D, Tosner J, Jacobsson B. Soluble Toll-like receptor 1 family members in the amniotic fluid of women with preterm prelabor rupture of the membranes. J Matern-Fetal Neo M. Sep;25(9):1699-704. 2012.
  61. Kacerovsky M, Andrys C, Hornychova H, Pliskova L, Lancz K, Musilova I, Drahosova M, Bolehovska R, Tambor V, Jacobsson B. Amniotic fluid soluble Toll-like receptor 4 in pregnancies complicated by preterm prelabor rupture of the membranes. J Matern-Fetal Neo M. Jul;25(7):1148-55. 2012.
  62. Kacerovsky M, Musilova I, Khatibi A, Skogstrand K, Hougaard DM, Tambor V, Tosner J, Jacobsson B. Intraamniotic inflammatory response to bacteria: analysis of multiple amniotic fluid proteins in women with preterm prelabor rupture of membranes. J Matern-Fetal Neo M. Oct;25(10):2014-9. 2012.
  63. Cobo T, Kacerovsky M, Palacio M, Hornychova H, Hougaard DM, Skogstrand K, Jacobsson B. A prediction model of histological chorioamnionitis and funisitis in preterm prelabor rupture of membranes: analyses of multiple proteins in the amniotic fluid. J Matern-Fetal Neo M. Oct;25(10):1995-2001. 2012.
  64. Kacerovsky M, Vavrova J, Musilova I, Lesko D, Flidrova E, Andrys C, Hornychova H, Dosedla E, Jacobsson B. Umbilical cord blood levels of cortisol and dehydroepiandrosterone sulfate in preterm prelabor rupture of membrane pregnancies complicated by the presence of histological chorioamnionitis. J Matern-Fetal Neo M. Oct;25(10):1889-94. 2012.
  65. Cobo T, Kacerovsky M, Holst RM, Hougaard DM, Skogstrand K, Wennerholm UB, Henrik Hagberg, Jacobsson B. Intra-amniotic inflammation predicts microbial invasion of the amniotic cavity but not spontaneous preterm delivery in preterm prelabor membrane rupture. Acta Obstet Gyn Scan. Aug;91(8):930-5. 2012.
  66. Khatibi A, Brantsater AL, Sengpiel V, Kacerovsky M, Magnus P, Morken NH, Myhre R, Gunnes N, Jacobsson B. Prepregnancy maternal body mass index and preterm delivery. Am J Obstet Gynecol. Sep;207(3):212.e1-7. 2012.
  67. Musilova I, Kacerovsky M, Hornychova H, Kostal M, Jacobsson B. Pulsation of the fetal splenic vein – a potential ultrasound marker of histological chorioamnionitis and funisitis in women with preterm prelabor rupture of membranes. Acta Obstet Gyn Scan. Sep;91(9):1119-23. 2012.
  68. Englund-Ögge L, Brantsæter AL, Haugen M, Sengpiel V, Khatibi A, Myhre R, Myking S, Meltzer HM, Kacerovsky M, Nilsen RM, Jacobsson B. Association between intake of artificially sweetened and sugar-sweetened beverages and preterm delivery: a large prospective cohort study. Am J Clin Nutr. Sep;96(3):552-9. 2012.
  69. Norton ME, Brar H, Weiss J, Karimi A, Laurent LC, Caughey AB, Rodriguez MH, Williams III J, Mitchell ME, Adair CD, Lee H, Jacobsson B, Tomlinson MW, Oepkes D, Hollemon D, Sparks AB, Oliphant A, Song K. Non-Invasive Chromosomal Evaluation (NICE) Study: results of a multicenter prospective cohort study for detection of fetal trisomy 21 and trisomy 18. Am J Obstet Gynecol. Aug;207(2):137.e1-8. 2012.
  70. Cobo T, Kacerovsky M, Palacio M, Hornychova H, Hougaard DM, Skogstrand K, Jacobsson B. Intra-amniotic inflammatory response in subgroups of women with preterm prelabor rupture of the membranes. PLoS One. 7(8):e43677. 2012.
  71. Kacerovsky M, Cobo T, Hornychova H, Andrys C, Ryska A, Musilova I, Kriz JT, Kostal M, Jacobsson B. Scavenger receptor for hemoglobin in preterm prelabor rupture of membranes pregnancies complicated by histological chorioamnionitis. J Matern-Fetal Neo M. Nov;25(11):2291-7. 2012.
  72. Alleman B*, Myking S*, Ryckman KK, Myhre R, Feingold E, Feenstra B, Geller F, Boyd HA, Shaffer JR, Zhang Q, Begum F, Crosslin D, Doheny K, Pugh E, Pay A, Ostensen IH, Morken N-H, Magnus P, Marazita ML, Jacobsson B*, Melbye M*, Murray JC*. No observed association for mitochondrial SNPs with preterm delivery and related outcomes. Pediatr Res. Nov;72(5):539-44. 2012.
    *Equal contribution.
  73. You F, Huo K, Wang R, Xu D, Deng J, Wei Y, Shi F, Liu H, Cheng G, Zhang Z, Yang P, Sun T, Wang X, Jacobsson B, Zhu C. Maternal mortality in Henan Province, China: Changes between 1996 and 2009. PLoS One. 2012;7(10):e47153. 2012.
  74. Tyrrell J, Huikari V, Christie JT, Cavadino A, Bakker R, Brion MJ, Geller F, Paternoster L, Myhre R, Potter C, Johnson PC, Ebrahim S, Feenstra B, Hartikainen AL, Hattersley AT, Hofman A, Kaakinen M, Lowe LP, Magnus P, McConnachie A, Melbye M, Ng JW, Nohr EA, Power C, Ring SM, Sebert SP, Sengpiel V, Taal HR, Watt GC, Sattar N, Relton CL, Jacobsson B, Frayling TM, Sørensen TI, Murray JC, Lawlor DA, Pennell CE, Jaddoe VW, Hypponen E, Lowe WL Jr, Jarvelin MR, Davey Smith G, Freathy RM; for the Early Growth Genetics (EGG) Consortium. Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) interacts with maternal self-reported smoking status during pregnancy to influence birth weight. Hum Mol Genet. Dec 15;21(24):5344-58. 2012.
  75. Cobo T, Tsiartas P, Kacerovsky M, Holst RM, Hougaard DM, Skogstrand K, Wennerholm UB, Hagberg H, Jacobsson B. Maternal inflammatory response to microbial invasion of the amniotic cavity: analysis of multiple proteins in the maternal serum. Acta Obstet Gyn Scan. Jan;92(1):61-8. 2013.
  76. Sengpiel V, Elind E, Bacelis J, Nilsson S, Grove J, Myhre R, Haugen M, Meltzer HM, Alexander J, Jacobsson B, Brantsæter AL. Maternal caffeine intake during pregnancy is associated with birth weight but not with gestational length: results from a large prospective observational cohort study. BMC Med. Feb 19;11(1):42. 2013.
  77. Andrys C, Kacerovsky M, Drahosova M, Musilova I, Pliskova L, Hornychova H, Prochazka M, Jacobsson B. Amniotic fluid soluble Toll-like receptor 2 in pregnancies complicated by preterm prelabor rupture of membranes. J Matern-Fetal Neo M. Mar;26(5):520-7. 2013.
  78. Kacerovsky M, Celec P, Vlkova B, Skogstrand K, Hougaard DM, Cobo T, Jacobsson B.  Amniotic fluid protein profiles of intraamniotic inflammatory response to Ureaplasma spp. and other bacteria. PLoS One. Mar;8(3):e60399. 2013
  79. Myking S*, Boyd HA*, Myhre R, Feenstra B, Jugessur A, Devold Pay AS, Østensen IH, Morken NH, Busch T, Ryckman KK, Geller F, Magnus P, Gjessing HK, Melbye M*, Jacobsson B*, Murray JC*. X-chromosomal maternal and fetal SNPs and the risk of spontaneous preterm delivery in a Danish/Norwegian genome-wide association study. PLoS One. Apr 16;8(4):e61781. 2013.
    *Equal contribution.
  80. Ahlin K, Himmelmann K, Hagberg G, Kacerovsky M, Cobo T, Wennerholm U-B, Jacobsson B. Non infectious risk factors for different types of cerebral palsy in term-born babies: a population-based, case-control study. BJOG. May;120(6):724-31. 2013.
  81. Kacerovsky M, Cobo T, Andrys C, Musilova I, Drahosova M, Hornychova H, Janku P, Jacobsson B. The fetal inflammatory response in subgroups of women with preterm prelabor rupture of the membranes. J Matern-Fetal Neo M. May;26(8):795-801. 2013.
  82. Musilova, I, Hornychova H, Kostal M, Jacobsson B, Kacerovsky M. Ultrasound measurement of the transverse diameter of the fetal thymus in pregnancies complicated by the preterm prelabor rupture of membranes. J Clin Ultrasound. Jun;41(5):283-9. 2013.
  83. Rietveld C A, Medland S E, Derringer J, Yang J, Martin N W, Abdellaoui A, Agrawal A, Albrecht E, Alizadeh B Z, Amin N, Barnard J, Baumeister S E, Benke K S, Bielak L F, Boatman J, Boyle P A, Davies G, de Leeuw C, Eklund N, Esko T, Evans D S, Fischer K, Gieger C, Gjessing H, Hägg S, Harris J, Hayward C, Holzapfel C, Ibrahim-Verbaas C A, Ingelsson E, Jacobsson B, Joshi P K, Jugessur A, Kaakinen M, Kanoni S, Kolcic I, Kristiansson K, Kutalik Z, Lahti J, Lee S H, Lin P, Liu Y, Lohman K, Loitfelder M, McMahon G, Vidal P M, Meirelles O, Milani L, Myhre R, Nuotio M-L, Oldmeadow C J, Petrovic K E, Peyrot W, Polašek O, Quaye L, Rice J P, Rizzi T S, Schmidt H, Schmidt R, Smith A V, Smith J A, Tanaka T, Terracciano A, van der Loos M J H M, Vitart V, Völzke H, Wellmann J, Yu L, Zhao W, Allik J, Attia J R, Bandinelli S, Bastardot F, Beauchamp J, Bennett D A, Berger K, Bierut L J, Boomsma D I, Bultmann U, Campbell H, Cherkas L, Chung M, Cucca F, de Andrade M, De Jager P L, De Neve J-E, Deary I J, Dedoussis G V, Deloukas P, Dimitriou M, Eiriksdottir G, Elderson M F, Eriksson J G, Evans D M, Faul J D, Ferrucci L, Garcia M E, Grönberg H, Gudnason V, Hall P, Harris J M, Harris T B, Hastie N D, Heath A C, Hernandez D G, Hoffmann W, Hofman A, Holle R, Holliday E G, Hottenga J-J, Iacono W G, Illig T, Järvelin M-R, Johannesson M, Kähönen M, Kaprio J, Kirkpatrick R M, Kowgier M, Latvala A, Launer L J, Lawlor D A, Lehtimäki T, Li J, Lichtenstein P, Lichtner P, Liewald D C, Madden P A, Magnusson P K E, Mäkinen T E, Masala M, McGue M, Metspalu A, Mielck A, Miller M B, Montgomery G W, Mukherjee S, Nyholt D R, Oostra B A, Palmer L J, Palotie A, Penninx B, Perola M, Peyser P A, Preisig M, Räikkönen K, Raitakari O T, Realo A, Ring S M, Ripatti S, Rivadeneira F, Rudan I, Salomaa V, Sarin A-P, Schlessinger D, Scott R J, Snieder H, St Pourcain B, Starr J M, Hoon Sul J, Surakka I, Svento R, Teumer A, van Rooij F J A, Van Wagoner D R, Vartiainen E, Viikari J, Vollenweider P, Vonk J M, Waeber G, Weir D R, Wichmann H-E, Widen E, Willemsen G, Wilson J F, Wright A F, Wright M J, Conley D, Davey-Smith G, Groenen P J F, Hofman A, Kardia S L R, Krueger R F, Laibson D, Martin N G, Meyer M N, Posthuma D, Thurik A R, Timpson N J, Uitterlinden A G, van Duijn C M, Visscher P M*, Benjamin D J*, Cesarini D*, Koellinger P D*. GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science. Jun 21;340(6139):1467-71. 2013.
    *Equal contribution.
  84. Verweij EJ, Jacobsson B, van Scheltema PA, de Boer MA, Boon E M J, Musci T, Westgren M, Song K, Oepkes D. European Non-Invasive Trisomy Evaluation (EU-NITE) Study: a multicenter prospective cohort study for noninvasive fetal trisomy 21 testing. Prenat Diagn. Jun 22;1-6. 2013.
  85. Ahlin K, Himmelmann K, Hagberg G, Kacerovsky M, Cobo T, Wennerholm U-B, Jacobsson B. Cerebral Palsy and perinatal infection in children born at term. Obstet Gynecol. Jul;122(1):41-49. 2013.
  86. Myhre R, Brantsæter AL, Myking S, Eggesbø M, Meltzer H M, Haugen M, Jacobsson B. Intake of Garlic and Dried fruits are associated with lower risk of spontaneous preterm delivery. J Nutr. Jul;143(7):1100-8. 2013.
  87. Cobo T, Kacerovsky M, Andrys C, Drahosova M, Musilova I, Hornychova H, Jacobsson B. Umbilical cord blood IL-6 as predictor of early-onset neonatal sepsis in women with preterm prelabour rupture of membranes. PLoS One. Jul24;8(7):e69341. 2013.
  88. Sengpiel V, Bacelis J, Myhre R, Myking S, Pay A, Haugen M, Brantsæter AL, Meltzer HM, Nilsen RM, Magnus P, Vollset SE, Nilsson S, Jacobsson B. Folic acid supplementation, dietary folate intake during pregnancy and risk for spontaneous preterm delivery: a prospective observational cohort study. BMC Pregnacy Childb. Aug 12;13:160. 2013.
  89. Devold Pay AS, Frøen JF, Staff A C, Jacobsson B, Gjessing HK. A new population-based reference curve for symphysis-fundus height. Acta Obst Gyn Scan. Aug;92(8):925-33. 2013.
  90. Sundqvist M, Osla V, Jacobsson B, Rudin A, Sävman K, Karlsson A. Cord blood neutrophils display a galectin-3 responsive phenotype accentuated by vaginal delivery. BMC Pediatr. Aug 21;13(1):128. 2013.
  91. Tsiartas P, Kacerovsky M, Musilova I, Hornychova H, Cobo T, Sävman K, Jacobsson B. The association between histological chorioamnionitis, funisitis and neonatal outcome in women with preterm prelabor rupture of membranes. J Matern-Fetal Neo M. Sep;26(13):1332-6. 2013.
  92. Kacerovsky M, Drahosova M, Krejsek J, Musilova I, Hornychova H, Matula V, Simetka O, Jacobsson B, Andrys C. Amniotic fluid CD200 levels in pregnancies complicated by preterm prelabor rupture of the membranes. J Matern Fetal Neo M. Sep;26(14):1416-24. 2013.
  93. Slavica L, Nordström I, Nurkkala-Karlsson M, Valadi H, Kacerovsky M, Jacobsson B, Eriksson K. TLR3 impairment in human newborns. J Leukoc Biol. Nov;94(5):1003-11. 2013.
  94. Bertelsen RJ, Brantsæter AL, Magnus MC, Haugen M, Myhre R, Jacobsson B, Longnecker MP, Meltzer HM, London SJ. Probiotic milk consumption in pregnancy and infancy and subsequent childhood allergic diseases. J Allergy Clin Immun. Jan;133(1):165-71. 2014.
  95. Cobo T,  Jacobsson B, Kacerovsky M, Hougaard DM, Skogstrand K, Gratacós E, Palacio M. Systemic and local inflammatory response in women with preterm prelabor rupture of membranes. PLoS One. Jan 21;9(1):e85277. 2014.
  96. Morken NH, Källen K, Jacobsson B. Predicting risk of spontaneous preterm delivery in women with a singleton pregnancy. Paediatr Perinat Epi. Jan;28(1):11-22. 2014.
  97. Englund-Ögge L, Brantsæter A-L, Sengpiel V, Haugen M, Bacelis J, Myhre R, Meltzer H M, Jacobsson B. Maternal dietary patterns and preterm delivery: results from large prospective cohort study. BMJ. Mar 4;348:g1446. 2014.
  98. Håkansson S, Källén K, Bullarbo M, Holmgren PÅ, Bremme K, Larsson A, Norman M, Norén H, Ortmark-Wrede C, Pettersson K, Saltvedt S, Sondell B, Tokarska M, von Vultee A, Jacobsson B. Real-time PCR-assay in the delivery suite for determination of group B streptococcal colonization in a setting with risk-based antibiotic prophylaxis. J Matern-Fetal Neo Med. Mar;27(4):328-32. 2014.
  99. Musilova I, Kacerovsky M, Andrys C, Kostal M, Slaba K, Jacobsson B. The fetal splenic vein flow pattern and fetal inflammatory response in the preterm prelabor rupture of membranes. J Matern-Fetal Neo Med. May;27(8):770-4. 2014.
  100. Kacerovsky M, Musilova I, Andrys C, Hornychova H, Pliskova L, Kostal M, Jacobsson B. Prelabor rupture of membranes between 34 and 37 weeks – the intraamniotic inflammatory response and neonatal outcomes. Am J Obstet Gynocol. Apr;210(4):325. 2014.
  101. Stokholm J, Schjørring S, Eskildsen CE, Pedersen L, Bischoff AL, Følsgaard N, Carson CG, Chawes BL, Bønnelykke K, Mølgaard A, Jacobsson B, Krogfelt KA, Bisgaard H. Antibiotic Use during Pregnancy Alters the Commensal Vaginal Microbiota. CMI. Jul;20(7):629-35. 2014.
  102. Kacerovsky M, Musilova I, Andrys C, Drahosova M, Hornychova H, Rezac A, Kostal M, Jacobsson B. Oligohydramnios in women with preterm prelabor rupture of membranes and adverse pregnancy and neonatal outcomes. PLoS One. Aug 29;9(8). 2014.
  103. Kacerovsky M, Musilova I, Hornychova H, Kutova R, Pilskova L, Kostal M, Jacobsson B. Bedside assessment of amniotic fluid interleukin-6 in preterm prelabor rupture of membranes. Am J Obstet Gynecol. Oct;211(4):385. 2014.
  104. Musilova I, Pliskova L, Kutova R, Hornychova H, Jacobsson B, Kacerovsky M. Ureaplasma species and Mycoplasma hominis in cervical fluid of pregnancies complicated by preterm prelabor rupture of membranes. J Matern-Fetal Neo Med. Nov;28:1-7. 2014.
  105. Brantsæter AL, Haugen M, Myhre R, Sengpiel V, Englund-Ögge L, Nielsen R M, Borgen I, Duarte-Salles T, Papadopoulou E, Vejrup K, von Ruesten A, Hillesund E R, Birgisdottir B E, Magnus P, Trogstad L, Jacobsson B, Bacelis J, Myking S, Knutsen H K, Kvalem H E, Alexander J, Mendez M, Meltzer H M. Diet matters, particularly in pregnancy – Results from MoBa studies of maternal diet and pregnancy outcomes. Norwegian Journal of Epidemiology. Dec;24 (1-2): 63-77 2014.
  106. Kacerovsky M, Musilova I, Jacobsson B, Drahosova M, Hornychova H, Janku P, Prochazka M, Simetka O, Andrys C. Cervical fluid IL-6 and IL-8 levels in pregnancies complicated by preterm prelabor rupture of membranes. J Matern-Fetal Neo Med. Jan;28(2):134-40. 2015.
  107. Devold Pay AS, Wiik J, Backe B, Jacobsson B, Strandell A, Klovning A. Symphysis – fundus height measurement to predict small-for-gestational-age status at birth: a systematic review. BMC Pregnancy and Childbirth. Feb 10;15:22. 2015.
  108. van der Valk RJ*, Kreiner-Møller E*, Kooijman MN*, Guxens M*, Stergiakouli E*, Sääf A, Bradfield JP, Geller F, Hayes MG, Cousminer DL, Körner A, Thiering E, Curtin JA, Myhre R, Huikari V, Joro R, Kerkhof M, Warrington NM, Pitkänen N, Ntalla I, Horikoshi M, Veijola R, Freathy RM, Teo YY, Barton SJ, Evans DM, Kemp JP, St Pourcain B, Ring SM, Smith GD, Bergström A, Kull I, Hakonarson H, Mentch FD, Bisgaard H, Chawes B, Stokholm J, Waage J, Eriksen P, Sevelsted A, Melbye M; Early Genetics & Lifecourse Epidemiology (EAGLE) Consortium, van Duijn CM, Medina-Gomez C, Hofman A, de Jongste JC, Taal HR, Uitterlinden AG; Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Armstrong LL, Eriksson J, Palotie A, Bustamante M, Estivill X, Gonzalez JR, Llop S, Kiess W, Mahajan A, Flexeder C, Tiesler CM, Murray CS, Simpson A, Magnus P, Sengpiel V, Hartikainen AL, Keinanen-Kiukaanniemi S, Lewin A, Da Silva Couto Alves A, Blakemore AI, Buxton JL, Kaakinen M, Rodriguez A, Sebert S, Vaarasmaki M, Lakka T, Lindi V, Gehring U, Postma DS, Ang W, Newnham JP, Lyytikäinen LP, Pahkala K, Raitakari OT, Panoutsopoulou K, Zeggini E, Boomsma DI, Groen-Blokhuis M, Ilonen J, Franke L, Hirschhorn JN, Pers TH, Liang L, Huang J, Hocher B, Knip M, Saw SM, Holloway JW, Melén E, Grant SF, Feenstra B, Lowe WL, Widén E, Sergeyev E, Grallert H, Custovic A, Jacobsson B, Jarvelin MR, Atalay M, Koppelman GH, Pennell CE, Niinikoski H, Dedoussis GV, McCarthy MI, Frayling TM, Sunyer J, Timpson NJ, Rivadeneira F, Bønnelykke K, Jaddoe VW; for the Early Growth Genetics (EGG) Consortium. A novel common variant in DCST2 is associated with length in early life and height in adulthood. Human Mol Genet.
    Feb 15;24(4):1155-68. 2015. *Equal contribution.
  109. Kacerovsky M, Musilova I, Jacobsson B, Drahosova M, Hornychova H, Janku P, Prochazka M, Simetka O, Andrys C. Vaginal fluid IL-6 and IL-8 levels in pregnancies complicated by preterm prelabor membrane ruptures. J Matern-Fetal Neo Med. Mar;28(4):392-8. 2015.
  110. Bry KJ, Jacobsson B, Nilsson S, Bry K. Gastric fluid cytokines are associated with chorioamnionitis and white blood cell counts in preterm infants. Acta Paediatr. Jun;104(6):575-80. 2015.
  111. Kuusela P, Jacobsson B, Söderlund M, Bejlum C, Almström E, Ladfors L, Hagberg H, Wennerholm U-B. Transvaginal sonographic evaluation of cervical length in the second trimester of asymptomatic singleton pregnancies, and the risk of preterm delivery. Acta Obst Gyn Scan. Jun;94(6):598-607. 2015.
  112. Norton M, Jacobsson B, Swamy GK, Laurent LC, Ranzini AC, Brar H, Tomlinson M, Pereira L, Spitz J, Hollemon D, Cuckle H, Musci TJ, Wapner RJ.
    Non-invasive EXamination of Trisomy using Directed Cell Free DNA Analysis: The NEXT Study. NEJM. Apr 23;372(17):1589-97. 2015.
  113. Musilova I, Pliskova L, Kutova R, Jacobsson B, Paterova P, Kacerovsky M. Streptococcus agalactiae in pregnancies complicated by preterm prelabor rupture of membranes. J Matern-Fetal Neo M. May 26:1-5. 2015: Epub ahead of print.
  114. Peyrot W J, Lee S H, Milaneschi Y, Abdellaoui A, Byrne E M, Esko T,
    de Geus E J C, Hemani G, Hottenga J J, Kloiber S, Levinson D F, Lucae S, Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium (Corporate Collaborator), Martin N G, Medland S E, Metspalu A, Milani L, Noethen M M, Potash J B, Rietschel M, Rietveld C A, Ripke S, Shi J, Social Science Genetic Association Consortium (Corporate Collaborator), Willemsen G, Zhu Z, Boomsma D I, Wray N R and Penninx B W J H. The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25 000 subjects. Mol Psychiatry. Jun;20(6):735-43. 2015.
  115. Musilova I, Kutová R, Pliskova L, Stepan M, Menon R, Jacobsson B, Kacerovsky M. Intraamniotic inflammation in women with preterm prelabor rupture of membranes. PLoS One. Jul 24;10(7). e0133929. 2015.
  116. Tsiartas P, Karcerovsky M, Hallingström M, Liman V, Cobo T, Jacobsson B. The effects of latency of time, centrifugation conditions, supernate filtration and addition of protease inhibitors on amniotic fluid interleukin-6 concentration. Am J Obstet Gynecol. Aug 213(2):247-8. 2015.
  117. Zhang G, Bacelis J, Lengyel C, Teramo K, Hallman M, Helgeland Ø, Johansson S, Myhre R, Sengpiel V, Njølstad PR, Jacobsson B, Muglia L. Assessing the Causal Relationship of Maternal Height on Birth Size and Gestational Age at Birth: A Mendelian Randomization Analysis. PLoS Medicine. Aug18;12(8) e1001865. 2015.
  118. Kacerovsky M, Musilova I, Stepan M, Andrys C, Drahosova M, Jacobsson B. Detection of intraamniotic inflammation in fresh and processed amniotic fluid samples with the interleukin-6 point of care test. Am J Obstet Gynecol. Sept 213(3):435-6. 2015.
  119. Paternoster L, Standl M, Waage J, Baurecht H, Hotze M, Strachan DP, Curtin JA, Bønnelykke K, Tian C, Takahashi A, Esparza-Gordillo J, Alves AC, Thyssen JP, den Dekker HT, Ferreira MA, Altmaier E, Sleiman PM, Xiao FL, Gonzalez JR, Marenholz I, Kalb B, Pino-Yanes M, Xu CJ, Carstensen L, Groen-Blokhuis MM, Venturini C, Pennell CE, Barton SJ, Levin AM, Curjuric I, Bustamante M, Kreiner-Møller E, Lockett GA, Bacelis J, Bunyavanich S, Myers RA, Matanovic A, Kumar A, Tung JY, Hirota T, Kubo M, McArdle WL, Henderson AJ, Kemp JP, Zheng J, Smith GD, Rüschendorf F, Bauerfeind A, Lee-Kirsch MA, Arnold A, Homuth G, Schmidt CO, Mangold E, Cichon S, Keil T, Rodríguez E, Peters A, Franke A, Lieb W, Novak N, Fölster-Holst R, Horikoshi M, Pekkanen J, Sebert S, Husemoen LL, Grarup N, de Jongste JC, Rivadeneira F, Hofman A, Jaddoe VW, Pasmans SG, Elbert NJ, Uitterlinden AG, Marks GB, Thompson PJ, Matheson MC, Robertson CF; Australian Asthma Genetics Consortium (AAGC), Ried JS, Li J, Zuo XB, Zheng XD, Yin XY, Sun LD, McAleer MA, O’Regan GM, Fahy CM, Campbell L, Macek M, Kurek M, Hu D, Eng C, Postma DS, Feenstra B, Geller F, Hottenga JJ, Middeldorp CM, Hysi P, Bataille V, Spector T, Tiesler CM, Thiering E, Pahukasahasram B, Yang JJ, Imboden M, Huntsman S, Vilor-Tejedor N, Relton CL, Myhre R, Nystad W, Custovic A, Weiss ST, Meyers DA, Söderhäll C, Melén E, Ober C, Raby BA, Simpson A, Jacobsson B, Holloway JW, Bisgaard H, Sunyer J, Probst-Hensch NM, Williams LK, Godfrey KM, Wang CA, Boomsma DI, Melbye M, Koppelman GH, Jarvis D, McLean WH, Irvine AD, Zhang XJ, Hakonarson H, Gieger C, Burchard EG, Martin NG, Duijts L, Linneberg A, Jarvelin MR, Nöthen MM, Lau S, Hübner N, Lee YA, Tamari M, Hinds DA, Glass D, Brown SJ, Heinrich J, Evans DM, Weidinger S; EArly Genetics and Lifecourse Epidemiology (EAGLE) Eczema Consortium, Australian Asthma Genetics Consortium (AAGC). Multi-ancestry genome-wide association of study 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. Nat Genet. Dec;47(12):1449-56. 2015.
  120. Davidson T, Iwarsson E, Jacobsson B, Dagerhamn J, Heibert Arnhild M. Costs And Cost-Effectiveness Of Non-Invasive Prenatal Diagnosis (Nipt) For Detection Of Trisomy 21 In Sweden. Value Health. Nov;18(7)A352. 2015.
  121. Stokowski R, Wang E, White K, Batey A, Jacobsson B, Brar H, Balanarasimha M, Hollemon D, Sparks A, Nicolaides K, Musci TJ. Clinical performance of non-invasive prenatal testing (NIPT) using targeted cell-free DNA analysis in maternal plasma with microarrays or next generation sequencing (NGS) is consistent across multiple controlled clinical studies. Prenatal diagnosis. Dec:35(12):1243–1246. 2015.
  122. Felix JF, Bradfield JP, Monnereau C, van der Valk RJ, Stergiakouli E, Chesi A, Gaillard R, Feenstra B, Thiering E, Kreiner-Møller E, Mahajan A, Pitkänen N, Joro R, Cavadino A, Huikari V, Franks S, Groen-Blokhuis MM, Cousminer DL, Marsh JA, Lehtimäki T, Curtin JA, Vioque J, Ahluwalia TS, Myhre R, Price TS, Vilor-Tejedor N, Yengo L, Grarup N, Ntalla I, Ang W, Atalay M, Bisgaard H, Blakemore AI, Bonnefond A, Carstensen L; Bone Mineral Density in Childhood Study (BMDCS); Early Genetics and LifecourseEpidemiology (EAGLE) consortium, Eriksson J, Flexeder C, Franke L, Geller F, Geserick M, Hartikainen AL, Haworth CM, Hirschhorn JN, Hofman A, Holm JC, Horikoshi M, Hottenga JJ, Huang J, Kadarmideen HN, Kähönen M, Kiess W, Lakka HM, Lakka TA, Lewin AM, Liang L, Lyytikäinen LP, Ma B, Magnus P, McCormack SE, McMahon G, Mentch FD, Middeldorp CM, Murray CS, Pahkala K, Pers TH, Pfäffle R, Postma DS, Power C, Simpson A, Sengpiel V, Tiesler CM, Torrent M, Uitterlinden AG, van Meurs JB, Vinding R, Waage J, Wardle J, Zeggini E, Zemel BS, Dedoussis GV, Pedersen O, Froguel P, Sunyer J, Plomin R, Jacobsson B, Hansen T, Gonzalez JR, Custovic A, Raitakari OT, Pennell CE, Widén E, Boomsma DI, Koppelman GH, Sebert S, Järvelin MR, Hyppönen E, McCarthy MI, Lindi V, Harri N, Körner A, Bønnelykke K, Heinrich J, Melbye M, Rivadeneira F, Hakonarson H, Ring SM, Smith GD, Sørensen TI, Timpson NJ, Grant SF, Jaddoe VW; Early Growth Genetics (EGG) Consortium; Bone Mineral Density in Childhood study BMDCS. Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Human Molecular Genetics. Jan 15;25(2):389-403. 2016.
  123. Zambrana IM, Vollrath ME, Sengpiel V, Jacobsson B, Ystrom E.
    Preterm delivery and risk for early language delays: a siblings-control cohort study. Int J Epidemiol Feb 45(1):151-159. 2016.
  124. Ahlin K, Himmelmann K, Nilsson S, Sengpiel V, Jacobsson B. Antecedents of cerebral palsy according to severity of motor impairment. Acta Obstet Gynecol Scand. Jul 95(7):793-802. 2016.
  125. Tyrrell J, Richmond RC, Palmer TM, Feenstra B, Rangarajan J, Metrustry S, Cavadino A, Paternoster L, Armstrong LL, De Silva NMG, Wood AR, Horikoshi M, Geller F, Myhre R, Bradfield JP, Kreiner-Møller E, Huikari V, Painter JN, Hottenga J-J, Allard C, Berry DJ, Bouchard L, Das S, Evans DM, Hakonarson H, Hayes MG, Heikkinen J, Hofman A, Knight B, Lind PA, McCarthy MI, McMahon G, Medland SE, Melbye M, Morris AP, Nodzenski M, Reichetzeder C, Ring SM, Sebert S, Sengpiel V, Sørensen TIA, Steegers EA, Willemsen G, De Geus EJ, Martin NG, Spector TD, Power C, Järvelin M-R, Bisgaard H, Grant SFA, Nohr EA, Jaddoe VW, Jacobsson B, Murray JC, Hocher B, Hattersley AT, Scholtens DM, Davey-Smith G, Hivert M-F, Felix JF, Hyppönen E, Lowe Jr. WL, Frayling TM, Lawlor DA, Freathy RM; Early Growth Genetics (EGG) Consortium. Genetic evidence for causal relationships between maternal obesity-related traits and birth weight. JAMA Mar 15;315(11):1129-1140. 2016.
  126. Stepan M, Cobo T, Musilova I, Hornychova H, Jacobsson B, Kacerovsky M. Maternal Serum C-Reactive Protein in Women with Preterm Prelabor Rupture of Membranes. PLoS One. Mar 4;11(3):e0150217. 2016.
  127. Laudanski P, Charkiewicz K, Kisielewski R, Kuc P, Koc-Zorawska E, Raba G, Kraczkowski J, Dymicka-Piekarska V, Chabowski A, Kacerovsky M, Jacobsson B, Zabielski P, Blachnio-Zabielska A. Plasma C16-Cer levels are increased in patients with preterm labor. Prostaglandins Other Lipid Mediat. Mar 123:40-5. 2016.
  128. Musilova I, Andrys C, Drahosova M, Soucek O, Kutova R, Pliskova L, Spacek R, Laudanski P, Jacobsson B, Kacerovsky M. Amniotic fluid calreticulin in pregnancies complicated by the preterm prelabor rupture of membranes. J Matern Fetal Neonatal Med. Dec 29(24):3921-3929.
  129. Vinturache AE, Gyamfi-Bannerman C, Hwang J, Mysorekar IU,
    Jacobsson B; Preterm Birth International Collaborative (PREBIC). Maternal microbiome – A pathway to preterm birth. Semin Fetal Neonatal Med. Apr 21(2):94-99. 2016.
  130. Rodríguez-Trujillo A, Cobo T, Vives I, Bosch J, Kacerovsky M, Posadas DE, Ángeles MA, Gratacós E, Jacobsson B, Palacio M. Gestational age is more important for short-term neonatal outcome than microbial invasion of the amniotic cavity or intra-amniotic inflammation in preterm prelabor rupture of membranes. Acta Obstet Gynecol Scand. Aug 95(8):926-933. 2016.
  131. Jørgensen JS, Jacobsson B, Vinter CA, Lamont RF, Maršál K. Ingemar Ingemarsson Memorial Symposium on preterm delivery at the XXI FIGO World Congress. Acta Obstet Gynecol Scand. May 95(5):495-500. 2016.
  132. Hallingström M, Lenco J, Vajrychova M, Link M, Tambor V, Liman V, Bullarbo M, Nilsson S, Tsiartas P, Cobo T, Kacerovsky M, Jacobsson B. Proteomic Analysis of Early Mid-Trimester Amniotic Fluid Does Not Predict Spontaneous Preterm Delivery. PLoS One. May 23;11(5):e0155164. 2016.
  133. Okbay A, Beauchamp JP, Fontana MA, Lee JJ, Pers TH, Rietveld CA, Turley P, Chen GB, Emilsson V, Meddens SF, Oskarsson S, Pickrell JK, Thom K, Timshel P, de Vlaming R, Abdellaoui A, Ahluwalia TS, Bacelis J, Baumbach C, Bjornsdottir G, Brandsma JH, Pina Concas M, Derringer J, Furlotte NA, Galesloot TE, Girotto G, Gupta R, Hall LM, Harris SE, Hofer E, Horikoshi M, Huffman JE, Kaasik K, Kalafati IP, Karlsson R, Kong A, Lahti J, van der Lee SJ, deLeeuw C, Lind PA, Lindgren KO, Liu T, Mangino M, Marten J, Mihailov E, Miller MB, van der Most PJ, Oldmeadow C, Payton A, Pervjakova N, Peyrot WJ, Qian Y, Raitakari O, Rueedi R, Salvi E, Schmidt B, Schraut KE, Shi J, Smith AV, Poot RA, St Pourcain B, Teumer A, Thorleifsson G, Verweij N, Vuckovic D, Wellmann J, Westra HJ, Yang J, Zhao W, Zhu Z, Alizadeh BZ, Amin N, Bakshi A, Baumeister SE, Biino G, Bønnelykke K, Boyle PA, Campbell H, Cappuccio FP, Davies G, De Neve JE, Deloukas P, Demuth I, Ding J, Eibich P, Eisele L, Eklund N, Evans DM, Faul JD, Feitosa MF, Forstner AJ, Gandin I, Gunnarsson B, Halldórsson BV, Harris TB, Heath AC, Hocking LJ, Holliday EG, Homuth G, Horan MA, Hottenga JJ, de Jager PL, Joshi PK, Jugessur A, Kaakinen MA, Kähönen M, Kanoni S, Keltigangas-Järvinen L, Kiemeney LA, Kolcic I, Koskinen S, Kraja AT, Kroh M, Kutalik Z, Latvala A, Launer LJ, Lebreton MP, Levinson DF, Lichtenstein P, Lichtner P, Liewald DC; LifeLines Cohort Study, Loukola A, Madden PA, Mägi R, Mäki-Opas T, Marioni RE, Marques-Vidal P, Meddens GA, McMahon G, Meisinger C, Meitinger T, Milaneschi Y, Milani L, Montgomery GW, Myhre R, Nelson CP, Nyholt DR, Ollier WE, Palotie A, Paternoster L, Pedersen NL, Petrovic KE, Porteous DJ, Räikkönen K, Ring SM, Robino A, Rostapshova O, Rudan I, Rustichini A, Salomaa V, Sanders AR, Sarin AP, Schmidt H, Scott RJ, Smith BH, Smith JA, Staessen JA, Steinhagen-Thiessen E, Strauch K, Terracciano A, Tobin MD, Ulivi S, Vaccargiu S, Quaye L, van Rooij FJ, Venturini C, Vinkhuyzen AA, Völker U, Völzke H, Vonk JM, Vozzi D, Waage J, Ware EB, Willemsen G, Attia JR, Bennett DA, Berger K, Bertram L, Bisgaard H, Boomsma DI, Borecki IB, Bültmann U, Chabris CF, Cucca F, Cusi D, Deary IJ, Dedoussis GV, van Duijn CM, Eriksson JG, Franke B, Franke L, Gasparini P, Gejman PV, Gieger C, Grabe HJ, Gratten J, Groenen PJ, Gudnason V, van der Harst P, Hayward C, Hinds DA, Hoffmann W, Hyppönen E, Iacono WG, Jacobsson B, Järvelin MR, Jöckel KH, Kaprio J, Kardia SL, Lehtimäki T, Lehrer SF, Magnusson PK, Martin NG, McGue M, Metspalu A, Pendleton N, Penninx BW, Perola M, Pirastu N, Pirastu M, Polasek O, Posthuma D, Power C, Province MA, Samani NJ, Schlessinger D, Schmidt R, Sørensen TI, Spector TD, Stefansson K, Thorsteinsdottir U, Thurik AR, Timpson NJ, Tiemeier H, Tung JY, Uitterlinden AG, Vitart V, Vollenweider P, Weir DR, Wilson JF, Wright AF, Conley DC, Krueger RF, Davey Smith G, Hofman A, Laibson DI, Medland SE, Meyer MN, Yang J, Johannesson M, Visscher PM, Esko T, Koellinger PD, Cesarini D, Benjamin DJ.
    Genome-wide association study identifies 74 loci associated with educational attainment. Nature. May 11;533(7604):539-542. 2016.
  134. Pay A, Frøen JF, Staff AC, Jacobsson B, Gjessing HK. Prediction of small-for-gestational-age status by symphysis-fundus height: a registry-based population cohort study. BJOG Jun 123(7):1167-1173. 2016.
  135. Musilova I, Andrys C, Drahosova M, Soucek O, Stepan M, Bestvina T, Spacek R, Jacobsson B, Cobo T, Kacerovsky M. Intraamniotic inflammation and umbilical cord blood interleukin-6 concentrations in pregnancies complicated by preterm prelabor rupture of membranes. J Matern Fetal Neonatal Med. Jun 20:1-11. 2016. Epub a head of print.
  136. Stepan M, Cobo T, Maly J, Navratilova M, Musilova I, Hornychova H, Jacobsson B, Kacerovsky M. Neonatal outcomes in subgroups of women with preterm prelabor rupture of membranes before 34 weeks. J Matern-Fetal Neo M.
    Jul 29(14):2373-2377. 2016.
  137. Musilova I, Bestvina T, Hudeckova M, Michalec I, Cobo T, Jacobsson B, Kacerovsky M. Vaginal fluid interleukin-6 concentrations as a point-of-care test is of value in women with preterm prelabor rupture of membranes. Am J Obstet Gynecol. Jul. 2016. Epub a head of print.
  138. Musilova I, Bestvina T, Hudeckova M, Michalec I, Cobo T, Jacobsson B, Kacerovsky M. Vaginal fluid IL-6 concentrations as a point-of-care test is of value in women with preterm PROM. Am J Obstet Gynecol. Jul. 2016. Epub a head of print.
  139. Bacelis J, Juodakis J, Sengpiel V, Zhang G, Myhre R, Muglia LJ, Nilsson S, Jacobsson B. Literature-Informed Analysis of a Genome-Wide Association Study of Gestational Age in Norwegian Women and Children Suggests Involvement of Inflammatory Pathways. PLoS One. Aug 4;11(8):e0160335. 2016.
  140. Bustamente M, Standl M, Bassat Q, Vilor-Tejedor N, Medina-Gomez C, Bonilla C, Ahluwalia TS, Bacelis J, Bradfield JP, Tiesler CM, Rivadeneira F, Ring S, Vissing NH, Fink NR, Jugessur A, Mentch FD, Ballester F, Kriebel J, Kiefte-de Jong JC, Wolsk HM, Llop S, Thiering E, Beth SA, Timpson NJ, Andersen J, Schulz H, Jaddoe VW, Evans DM, Waage J, Hakonarson H, Grant SF, Jacobsson B, Bønnelykke K, Bisgaard H, Davey Smith G, Moll HA, Heinrich J, Estivill X,
    Sunyer J. A genome-wide association meta-analysis of diarrhoeal disease in young children identifies FUT2 locus and provides plausible biological pathways. Hum Mol Genet. Aug 23. 2016. Epub a head of print.
  141. Stalberg C, Noda N, Polettini J, Jacobsson B, Menon R. Anti-inflammatory Elafin in human fetal membranes. J Perinat Med. Aug 31. 2016. Epub a head of print.
  142. Ferrero DM, Larson J, Jacobsson B, Di Renzo GC, Norman JE, Martin JN Jr, D’Alton M, Castelazo E, Howson CP, Sengpiel V, Bottai M, Mayo JA, Shaw GM, Verdenik I, Tul N, Velebil P, Cairns-Smith S, Rushwan H, Arulkumaran S, Howse JL, Simpson JL. Cross-Country Individual Participant Analysis of 4.1 Million Singleton Births in 5 Countries with Very High Human Development Index Confirms Known Associations but Provides No Biologic Explanation for 2/3 of All Preterm Births. PLoS One. Sep 13;11(9):e0162506. 2016.
  143. Musilova I, Andrys C, Drahosova M, Soucek O, Pliskova L, Stepan M, Bestvina T, Maly J, Jacobsson B, Kacerovsky M. Amniotic fluid cathepsin-G in pregnancies complicated by the preterm prelabor rupture of membranes. J Matern Fetal Neonatal Med. Sep 21:1-28. 2016. Epub a head of print.
  144. Brubaker D, Liu Y, Wang J, Tan H, Zhang G, Jacobsson B, Muglia L, Mesiano S, Chance MR. Finding Lost Genes in GWAS via Integrative -Omics Analysis Reveals Novel Sub-networks Associated with Preterm Birth. Hum Mol Genet. Sep 23. 2016. Epub a head of print.
  145. Vollrath ME, Sengpiel V, Landolt MA, Jacobsson B, Latal B. Is maternal trait anxiety a risk factor for late preterm and early term deliveries? BMC Pregnancy Childbirth. Sep 29;16(1):286. 2016.
  146. Musilova I, Andrys C, Drahosova M, Hornychova H, Jacobsson B, Menon R, Laudanski P, Stepan M, Bestvina T, Kacerovsky M. Amniotic fluid prostaglandin E2 in pregnancies complicated by preterm prelabor rupture of the membranes.
    J Matern-Fetal Neo M. Sep 29(18):2915-2923. 2016.
  147. Middeldorp CM, Hammerschlag AR, Ouwens KG, Groen-Blokhuis MM, St Pourcain B, Greven CU, Pappa I, Tiesler CM, Ang W, Nolte IM, Vilor-Tejedor N, Bacelis J, Ebejer JL, Zhao H, Davies GE, Ehli EA, Evans DM, Fedko IO, Guxens M, Hottenga JJ, Hudziak JJ, Jugessur A, Kemp JP, Krapohl E, Martin NG, Murcia M, Myhre R, Ormel J, Ring SM, Standl M, Stergiakouli E, Stoltenberg C, Thiering E, Timpson NJ, Trzaskowski M, van der Most PJ, Wang C; EArly Genetics and Lifecourse Epidemiology (EAGLE) Consortium, Psychiatric Genomics Consortium ADHD Working Group, Nyholt DR, Medland SE, Neale B, Jacobsson B, Sunyer J, Hartman CA, Whitehouse AJ, Pennell CE, Heinrich J, Plomin R, Davey Smith G, Tiemeier H, Posthuma D, Boomsma DI. A Genome-Wide Association Meta-Analysis of Attention-Deficit/Hyperactivity Disorder Symptoms in Population-Based Pediatric Cohorts. J Am Acad Child Adolesc Psychiatry. Oct 55(10):896-905. 2016.
  148. Kacerovsky M, Pliskova L, Skogstrand K, Hougaard D, Bolehovska R. Tosner J, Jacobsson B. Microbial load of genital mycoplasmas and intensity of intraamniotic inflammation: analysis of multiple amniotic fluid proteins. J Matern-Fetal Neo M. In Press.

Papers under editorial consideration in international journals
  1. Feenstra B, Cavadino A, Tyrrell J, McMahon G, Nodzenski M, Horikoshi M, Geller F, Myhre R, Richmond RC, Paternoster L, Bradfield JP, Kreiner-Møller E, Huikari V, Metrustry S, Lunetta KL, Painter JN, Hottenga J-J, Allard C, Barton SJ, Espinosa A, Marsh JA, Potter C, Ang W, Berry DJ, Bouchard L, Das S, Hakonarson H, Heikkinen J, Hocher B, Hofman A, Inskip HM, Kogevinas M, Lind PA, Marullo L, Medland SE, Murray JC, Nohr EA, Reichetzeder C, Ring SM, Santa-Marina L, Scholtens DM, Sebert S, Sengpiel V, Steegers EA, Willemsen G, Relton CL, Pennell CE, Chatzi L, Estivill X, Holloway JW, Boomsma DI, Montgomery GW, Murabito JM, Spector TD, Power C, Järvelin M-R, Bisgaard H, Grant SFA, Sørensen TIA, Jaddoe VW, Jacobsson B, Melbye M, McCarthy MI, Hattersley AT, Hayes MG, Evans DM, Hivert M-F, Felix JF, Hyppönen E, Lowe Jr WL, Lawlor DA, Frayling TM, Freathy RM. Genome-wide association study identifies a maternal fasting glucose variant associated with offspring birth weight.

Papers under preparation for international journals
  1. Allvin K, Niklasson A, Ankarberg-Lindgren C, Jacobsson B, Dahlgren J. Estradiol, testosterone and IGF-1 in umbilical cord blood – correlations to gender, gestational age, size at birth and hypertensive disorders of pregnancy.
  2. Sävman K, Doversjö T, Karlsson A, Nilsson U, Wennerholm UB, Holst RM, Hagberg H, Jacobsson B. Galectin-3 and activation of oxygen free radicals in preterm labor and preterm prelabor rupture of membranes.
  3. Nordqvist M, Myhre, R Bacelis J, Brantsaeter A-L, Jacobsson B, Sengpiel V. Probiotic consumtion before and during pregnancy and risk of preeclampsia and preterm delivery.
  4. Hallingström M, Kacerovsky M, Cobo T, Bullarbo M, Tsiartas P, Vlkova B, Celek P and Jacobsson B. Analysis of bacterial DNA in amniotic fluid at early midtrimester amniocentesis in relation to spontaneous preterm delivery.
  5. Hallingström M, Kacerovsky M, Cobo T, Skogstrand K, Hougaard DM, Holst R-M, Bullarbo M, Tsiartas P, Jacobsson B. Candidate protein levels in amniotic fluid at early mid-trimester amniocentesis in relation to spontaneous preterm delivery.
  6. Montenegro-Burke JR, Rogers LM, Hallingström M, Kacerovsky M, Jacobsson B, McLean JA, Aronoff DM. High-dimensional untargeted metabolomics strategy for assessing markers of preterm birth from amniotic fluid.
  7. Jacobsson B, Sengpiel V, Nilsson S, Hallingström M, Elfvin A, Brantsaeter A-L, Nordquist M, Myhre R, Cobo T. Immunological and inflammatory response after antenatal supplementation with Lactobacillus rhamnosus in low-risk pregnant women.
Original papers published in national journals (not in English)
  1. Aladdin B, Jacobsson B, Sandberg K, Lilja H. Oväntad förlossning utanför sjukhuset – hur går det? Sex års erfarenheter från Göteborgsregionen och förslag till riktlinjer för handläggning. Läkartidningen. 101; 3148-50. 2004.

Commentary
  1. Jacobsson B. Intra-amniotic infection and inflammation in preterm birth – is bacteria always the connection? Invited commentary. Pediatr Res. 57. 473-4. 2005.
Reviews
  1. Jacobsson B, Wide-Swensson D. Incarceration of the retroverted gravid uterus–a review. Acta Obstet Gyn Scan. 78. 665-8. 1999.
  2. Jacobsson B, Hagberg G. Antenatal risk factors for cerebral palsy. Best Pract Res Cl Ob. 18. 425-36. 2004.
  3. Jacobsson B. Infectious and inflammatory mechanisms in preterm birth and cerebral palsy. Eur J Obstet Gyn R B. 115. 159-160. 2004.
  4. Hagberg H, Mallard C, Jacobsson B. Role of cytokines in preterm labour and brain injury. BJOG: Int J Obstet Gy. 112. 16-8. 2005.
  5. Larsson PG, Bergström M, Forsum U, Jacobsson B, Strand A, Wölner-Hansen P. Bacterial vaginosis. Transmission, role in genital tract infection and pregnancy outcome: an enigma. APMIS. Apr;113(4): 233-45. 2005.
  6. Hagberg H, Jacobsson B. Braininjury in preterm infants – what can the obstetrician do? Early Hum Dev. 81. 231-235. 2005.
 Letters
  1. Vogel I, Kesmodel U, Rasmussen S, Langhoff-Roos J, Jacobsson B. Preterm delivery in primiparous women at low risk: Preterm birth or delivery? Study authors suggest new terms. BMJ. 332. 1094. 2006.
  2. Brantsæter AL, Jacobsson B. Intake of probiotic food and risk of preeclampsia in primiparous women. Am J Epidemiol. Correspondence. 175(5):477. 2012.
  3. Tsiartas P, Holst RM, Wennerholm UB, Hagberg H, Hougaard D, Skogstrand K, Pearce B, Thorsen P, Kacerovsky M, Jacobsson B. Prediction of spontaneous preterm delivery in women with threatened preterm labour: a prospective cohort study of multiple proteins in maternal serum. BJOG. Correspondence. Nov;119(12):1544-45. 2012.
  4. Englund-Ögge L, Brantsæter AL, Haugen M, Sengpiel V, Khatibi A, Myhre R, Myking S, Meltzer HM, Kacerovsky M, Nilsen RM, Jacobsson B. Association between intake of artificially sweetened and sugar-sweetened beverages and preterm delivery: a large prospective cohort study. Am J Clin Nutr. Correspondence. Jan 97:1 224-5. 2013.
  5. Cobo T, Kacerovsky M, Jacobsson B. Amniotic fluid infection, inflammation, and colonization in preterm labor with intact membranes. Am J Obstet Gynecol. Correspondence Dec; 211(6):708. 2014.
Case reports
  1. Jacobsson B, Wide-Swensson D. Recurrent incarceration of the retroverted gravid uterus–a case report. Acta Obstet Gyn Scan. 78. 737. 1999.
  2. Karlsson MD, Jacobsson B. Intrauterine fetal death associated with Rothia dentocariosa: a case report. Am J Obstet Gynecol. 197. e6-7. 2007.
  3. Lode MS, Jacobsson B. Delayed delivery in twins: an infectious abortion and a subsequent preterm delivery without histological signs of chorioamnionitis. Acta Obstet Gyn Scan. Mar;92(3):362-4. 2013.
  4. Kolnes K, Sundalsfoll S, Jacobsson B. Et uvanlig bifunn ved CT av bekken. Journal of the Norwegian Medical Association. 2014
Scientific papers published in national journals (not in English)
  1. Jacobsson B. Hög maternell ålder som obstetrisk riskfaktor. Svensk förening för obstetrik och gynekologi, Medlemsblad. Nummer 2. 2000.
  2. Jacobsson B. Infektioner orsak till för tidig födsel och neurologiskt handikapp. Läkartidningen 100. 2576. 2003.
  3. Jacobsson B. Mortalitet vid sätesförlossning i Sverige. Socialstyrelsens publikationer. Svenska Sätesstudiegruppen.
  4. Jacobsson B. Cerebral pares är associerad med avvikande födelsevikter. Läkartidningen. 101(18); 1595. 2004.
  5. Hagberg H, Jacobsson B. Korioamnionit – riskfaktor för cerebral pares hos barn som föds i fullgången tid. Medical Commentary. Läkartidningen. 101; 2542. 2004.
  6. Morken NH, Jacobsson B. Vaginal progesteronbehandling i graviditet forebygger ikke for tidlig fødsel. Tidsskr Nor Laegeforen. May 24;136(9):794. 2016.
  7. Jacobsson B, Hagberg H, Wennerholm U-B. Vaginalt progesteron förhindrade inte förtidsbörd eller fosterdöd. Läkartidningen 113:12-13. 2016.
  8. Jacobsson B, Sengpiel V. Överviktiga kvinnor får större barn – sannolikt ett kausalsamband. Läkartidningen 113:18-19. 2016.
  9. Jacobsson B, Munthe C, Saltvedt S, Carlsson Y, Lindgren P, Iwarsson E. NIPT ett genombrott i fosterdiagnostiken. Träffsäker metod ger färre invasive undersökningar – men gamla etiska frågor blir åter aktuella. Läkartidningen 113:22-23. 2016.
Text books and Book chapters
  1. Jacobsson B, Larsson P-G. Bakteriell vaginos under graviditet. Chapter in the book Bakteriell vaginos Editors Fossum U, Larsson P-G. 3M Pharma. Page 67-73. 2004.
  2. Jacobsson B. Cerebral palsy and fetal growth. Controversies in Obstetrics and Gynecology & Infertility. Ed: Ben-Rafael Z, Creatsas G, Shoham Z. 547-553. 2005.
  3. Larsson PG, Fossum U, Jacobsson B, Bakteriell Vaginos. Infpreg. 2006.
  4. Von Rosen I, Axelsson I, Eriksson BKG, Jacobsson B, Grupp A Streptokocker. Infpreg. 2007.
  5. Jacobsson B, Håkansson S. Grupp B Streptokocker. Infpreg. 2008, 2011.
  6. Jacobsson B, Hagberg H. Förtidsbörd. Chapter in Obstetrik. Ed: Hagberg H, Marsal K, Westgren M. Studentlitteratur. Sweden. 2008, 2014.
  7. Hakansson S, Jacobsson B, Holmgren P-Å. Streptokockinfektioner. Chapter in Obstetrisk Öppenvård. Ed: Marsal K, Grennert L. Natur och Kultur. Sweden. 2011.
Editorial board of specific tasks
  1. Caring for Tomorrow – the EFCNI White Paper on Maternal and Newborn Health